Usher Syndrome - Risk Factors

Usher Syndrome - Risk Factors

Recent research findings suggest that in some forms of retinal degeneration, prolonged, unprotected exposure to sunlight may accelerate vision loss. Therefore, The Foundation recommends that patients wear sunglasses and brimmed hats or visors when outdoors.

Some women feel that their vision loss progressed more rapidly during pregnancy. However, the effect of pregnancy on Usher syndrome has not been clinically studied.

Usher syndrome is an inherited, genetic disease. It is caused by mutations in genes that are active in the retina and in the ear. Gene mutations are programmed into your cells at the time of conception. Usher syndrome is not caused by injury, infection or exposure to any toxic substance.

Usher syndrome is an autosomal recessive disease. In autosomal recessive diseases, unaffected parents, who are carriers, have one gene with a disease-causing mutation paired with one normal gene. Each of their children then has a 25 percent chance (or 1 chance in 4) of inheriting the two diseased genes (one from each parent) needed to cause the disorder. Carriers are unaffected because they have only one copy of the gene.