Research Articles - Other Retinal Diseases
Two French research institutions — the Institut de la Vision and Institut Langevin — will receive nearly $16.5 million from the European Research Council (ERC) to advance state-of-the-art imaging technologies for gaining a better understanding of retinal diseases and developing sight-saving therapies.
The Foundation Fighting Blindness is providing $600,000 to a consortium of Israeli scientists working toward the ambitious goal of recruiting and genetically screening every person in Israel with an inherited retinal degenerative disease.
Eight years ago, Jim Schott told the staff at the Foundation Fighting Blindness that if they, indeed, wanted to launch a 5K walk program, he’d be honored to get the ball rolling by chairing the very first VisionWalk in his hometown of Orlando, Florida. But when the former superintendent of schools was told the goal was to raise $25,000, “I thought, ‘Oh my gosh, how are we going to raise that?’” he recalls. “It was a lot of money.”
At first blush, completely shutting down both copies of a gene might not seem like the best way to treat an inherited retinal disease. That’s because genes and the proteins they express are thought to be essential to the health and well-being of all cells in the body.
To advance the research and development of inherited retinal-disease therapies, the Foundation Fighting Blindness Clinical Research Institute (FFB CRI) and Sanofi, a global pharmaceutical company headquartered in France, have entered into a two-year agreement to regularly exchange scientific information.
In support of the fight to eradicate blindness, Foundation Fighting Blindness Chairman and Co-Founder Gordon Gund and his family announced a matching gift challenge they hope will result in millions of dollars in funds to accelerate pre-clinical, translational and clinical research for retinal degenerative diseases.
For the first time, researchers have used induced pluripotent stem cells — stem cells derived from the reprogramming of mature human cells — to create a three-dimensional retina with functional photoreceptors, the cells that make vision possible. The new model will enable scientists to better understand retinal development and function, and provide a powerful platform for creating and testing future therapies. Results from the study, led by M.