The Foundation Fighting Blindness (FFB) was established in 1971 by a passionate group of families driven to find treatments and cures for inherited retinal diseases that were affecting their loved ones. At that time, little was known about these blinding retinal degenerative diseases. Very little research was being done, and there were no clinical trials for potential treatments.
The Foundation’s goal was clear and focused: To drive the research that would lead to preventions, treatments, and vision restoration for the spectrum of degenerative retinal diseases, specifically macular degeneration – including age related macular degeneration, retinitis pigmentosa, Usher syndrome, Stargardt disease and Leber congenital amurosis (LCA). Together these conditions affect more than 10 million Americans and millions more throughout the world.
Today, the Foundation Fighting Blindness is the world’s leading private funder of retinal disease research. That funding has been a driving force behind the progress toward cures, including the identification of more than 250 genes linked to retinal disease, and the launch of 20 clinical trials for potential treatments.
On an annual basis, the Foundation Fighting Blindness and the Foundation’s Clinical Research Institute fund more than 100 research grants. The research projects are conducted by more than 150 research investigators at institutions, eye hospitals, and universities in the United States, Australia, England, France, Germany, The Netherlands, Italy, Israel, and Mexico.
More about the Foundation Fighting Blindness
- The Foundation funds innovative and cutting-edge research in promising areas such as genetics, gene and stem-cell therapies, retinal cell transplantation, and pharmaceutical and nutritional therapies.
- Foundation funding often provides the critical bridge between discovery research, proof of concept, and corporate investment in clinical trials and commercialization.
- The Foundation’s Clinical Research Institute (FFB-CRI) supports strategic relationships with commercial entities to advance the development of emerging compounds, i.e. potential drug treatments, for retinal degenerative diseases. If supported by research outcomes, FFB-CRI helps advance those treatments into viable commercial products available to patients.
- The Foundation is a 501©(3) charitable organization. Since its inception in September 1971, the Foundation has raised more than $700 million.
- The Foundation is an Accredited Charity by the Better Business Bureau Wise Giving Alliance. We are also pleased to be rated as 4 stars (top rating) for Accountability and Transparency by the Charity Navigator Website.
- On an average annual basis, the Foundation has invested approximately 75 percent of its budget in research and public health education programs. For more information about FFB finances go to http://www.blindness.org/financial-information
More Information about Retinal Degenerative Diseases
- Retinitis pigmentosa and Usher syndrome are inherited diseases commonly diagnosed during childhood or young adulthood. RP causes severe vision loss leading to legal and/or complete blindness. Children with Usher syndrome are born with varying degrees of deafness and later develop RP.
- Age-related macular degeneration (AMD) has both lifestyle and inherited risk factors. The condition is characterized by a progressive loss of central vision. AMD is the leading cause of blindness in adults over age 55 in the U.S. and other developed countries.
- The Foundation has 43 volunteer-led chapters across the U.S. These dedicated volunteers raise funds, increase public awareness, and provide support to their communities.
- The Foundation’s VisionWalk program holds fundraising walks in over 40 cities nationwide. Since its inception the FFB VisionWalk program has raised over $43 million for vision research.
- The Foundation provides information and outreach programs for patients, families and professionals. For more information about the Foundation or retinal degenerative diseases contact FFB at info@FFB.org.
Support our Mission
To Support the Foundation’s mission through a personal donation (Donate button) or to include the Foundation in your estate planning go to:http://myplantofightblindness.org/
Leading retinal research scientists praise the advances enabled by the Foundation.
- Morton F. Goldberg, MD
Wilmer Eye Institute, Johns Hopkins Univ. Hospital; served as Director of Wilmer for 15 years.
“FFB is an extraordinary organization. It has given hope to people who didn’t previously have hope, and it has supported the most important fundamental research in the retinal degenerations being carried out anywhere in the world today. Thanks to FFB, I have confidence that we will understand and be able to successfully treat many of these (retinal degenerative) diseases in the relatively near future... we are on the verge of human clinical trials and that would not have happened without the support of the FFB.”
- Stephen P. Daiger, PhD
Human Genetics Center, Univ. of Texas Health Science Center
“This incredible flowering of knowledge…was nursed into existence by the Foundation Fighting Blindness…If you were to take the thousand most important papers published in the past 15 years in the field of inherited retinal diseases, you would find that over 900 have authors supported by this Foundation.”
- Raymond D. Lund, PhD
FRS, Univ. of Utah Health Science Center, Moran Eye Center
“The Foundation has given a sense of hope to the families that are affected. They’ve pulled in scientists like me and others to be interested in the problems and apply our knowledge…it’s a proactive thing. The Foundation says we need this problem solved, how do we do it. There is no other foundation as focused as this one on these problems.”
- Donald J. Zack, MD, PhD
Wilmer Eye Institute, Johns Hopkins Medical School
“The Foundation, existing as an independent private entity, is able to very quickly fund young investigators and fund new and exciting projects. The Foundation has really played a major role in getting a number of important projects off the ground, which would not have happened without its support. The Foundation Fighting Blindness has stimulated interaction and collaboration between different scientific groups and centers, and it has funded a variety of research meetings that have helped scientists learn about areas outside their own, so they can do more productive and more powerful research.”
- Edwin Stone, MD, PhD
Univ. of Iowa Hospitals and Clinics, Dept. of Ophthalmology & Visual Sciences
“The Foundation Fighting Blindness has played a tremendous role in my development as an ophthalmologist and scientist and in the growing of our program. The Foundation has gathered together scientists from all over the world who are interested in a similar thing: to try to cure these diseases…People have to say, ‘yes I’m interested in helping this year, and I’m interested in helping next year because it just isn’t Ok for a child to be born missing one gene product in their retina.’ The Foundation has been a kind of ‘antenna’ conveying the resources from society to the scientist and they have done a very successful job of it.”
For more information, please contact the Foundation at:
7168 Columbia Gateway Drive, Suite 100
Columbia, MD 21046
800-683-5555 • 800-683-5551 TDD